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KMID : 0921620120420040357
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Journal of Bacteriology and Virology
2012 Volume.42 No. 4 p.357 ~ p.358
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Bacterial 23S Ribosomal RNA, a Ligand for Toll-like Receptor 13
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Manzoor Zahid
Koh Young-Sang
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Abstract
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Toll-like receptors are required for detection of pathogen-associated molecular patterns and play critical roles in protection of host from infection. Murine TLR13 was recently reported to be involved in recognition of bacterial 23S ribosomal RNA sequence that is the binding site of different antibiotics.
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KEYWORD
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Toll-like receptor, Toll-like receptor 13, Bacterial ribosomal RNA, Staphylococcus aureus
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